个人简介
研究方向聚焦于设计水凝胶生物药物递送系统并结合外场调控技术、干细胞治疗等解决生殖系统功能再生与病理微环境调控难题。近5年以第一/共同第一/通讯作者在Nat. Biomed. Eng.、Adv. Funct. Mater.、Bioact. Mater.、Biomaterials等学术期刊发表论文 SCI共计13篇 (其中JCR一区论文9篇,IF均大于10),另外在投 SCI 2篇,申请国家发明专利5项 (其中3项已授权);主持国家及省部级科研基金4项,包括国家自然科学基金青年项目、博士后科学基金面上、广东省基础与应用基础研究基金青年项目等,参与2项国家、广东省重点研发计划的研究课题。
研究领域
- 水凝胶生物材料的生殖医学工程应用
- 智能药物递送系统
- 组织再生过程中的血管化和纤维化调控
科研成果
| 项目名称 | 项目类型 |
| 调控I型胶原组装缓解基质硬化驱动的细胞机械激活以阻断子宫内膜纤维化正反馈 | 国家自然科学基金面上项目 |
| 递送MSCs并增强其旁分泌功能的可注射水凝胶微胶囊制剂用于卵巢早衰的治疗 | 国家自然科学基金-青年基金项目 |
| 水凝胶微半球制剂递送经血来源子宫内膜干细胞用于薄型子宫的再生修复 | 博士后基金面上项目 |
| 炎症调节的生物水凝胶薄膜用于防治宫腔黏连的研究 | 区域联合基金-青年基金项目 |
| 细胞外基质水凝胶微球递送干细胞用于治疗早发性卵巢功能不全的研究 | 中国博士后科学基金 |
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学术成果
- 1.Interventional Hydrogel Microsphere Controlled-Releasing Curcumin for Photothermal Therapy against Endometriosis.,Advanced Functional Materials,2024-03
- 2.3D-printed perfused models of the penis for the study of penile physiology and for restoring erectile function in rabbits and pigs.,Nature Biomedical Engineering,2025-03
- 3.An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions,Adv. Sci.,2026-09
- 4.Endometrial ECM-Modified Hemispherical Hydrogels Delivering MenSCs Promote Thin Endometrium Regeneration.,Adv. Healthc. Mater. ,2025-09
- 5.An Anti-Fibroblast Adhesion and Anti-Inflammatory Hydrogel Film Combined with VEGF for Intrauterine Adhesion Prevention.,Chem. Eng. J,2023-02
- 6.Ovarian extracellular matrix hydrogel microspheres increase the efficacy of stem cell treatment in premature ovarian insufficiency,The Innovation Life,2025-05
- 7.Magnetic mesoporous silica nanoparticles loaded with peptides for the targeted repair of cavernous nerve injury underlying erectile dysfunction,Biomaterials,2024-08
- 8.Biomaterial Strategies for the Application of Reproductive Tissue Engineering,Bioact. Mater,2021-11
- 9.High-Strength Hydroxyapatite Scaffolds with Minimal Surface Macrostructures for Load-Bearing Bone Regeneration,Adv. Funct. Mater.,2022-03
- 10.Functional Reconstruction of Injured Corpus Cavernosa Using 3D-Printed Hydrogel Scaffolds Seeded with HIF-1α-Expressing Stem Cells.,Nat. Commun.,2020-02
- 11.Molecular Recognition-Directed Site-Specific Release of Stem Cell Differentiation Inducers for Enhanced Joint Repair.,Biomaterials,2019-12
- 12.A Biomimetic Biphasic Osteochondral Scaffold with Layer-Specific Release of Stem Cell Differentiation Inducers for the Reconstruction of Osteochondral Defects.,Adv. Healthc. Mater. ,2020-04
- 13.Chlorophyllin-Containing Copolymers and Their Responsive Properties,ACS Appl. Bio Mater.,2023-05
社会兼职
- Regenerative Biomaterials期刊青年编委
教育经历
- 2016-09 至 2021-08,华南理工大学,博士研究生
- 2012-09 至 2016-06,郑州大学,理学学士
工作经历
- 2025-11,华东理工大学,特聘副研究员
- 2024-04 至 2025-09,广州医科大学附属第三医院,博士后工作
- 2021-11 至 2023-11,深圳市第二人民医院,博士后工作
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